Detonation - Aldrin - Singapore Tribal
Label: Muzik Magazine - MUZIKMAG82 / MAR02 • Format: CD Mixed • Country: UK • Genre: Electronic • Style: Progressive House, Tribal House, Tech House
Aldrin is an organochlorine insecticide that was widely used until the s, when it was banned in most countries. Aldrin is a member of the so-called "classic organochlorines" COC group of pesticides. It is a colourless solid. Before the ban, it was heavily used as a pesticide to treat seed and soil.
Fenesta Ca Lucive - Various - LOro Di Napoli and related "cyclodiene" pesticides a term for pesticides derived from Hexachlorocyclopentadiene became notorious as persistent organic pollutants. The structure formula of aldrin is C 12 H 8 Cl 6. The molecule has a molecular weight of Pure aldrin takes form as a white crystalline powder.
Though it is not soluble in water 0. Though it is rapidly converted to dieldrin by plants and bacteria, dieldrin maintains the same toxic effects and slow decay of aldrin. Aldrin does not react with mild acids or bases and is stable in an environment with a pH between 4 and 8.
Aldrin is not formed in nature. It is synthesized by combining hexachlorocyclopentadiene with norbornadiene in a Diels-Alder Sharks Back - Rude Kid - Are You Ready? to give the adduct.
Similarly, an isomer of aldrin, known as isodrinis produced by reaction of hexachloronobornadiene with cyclopentadiene. Aldrin is named after the German chemist Kurt Alderone of the coinventors of this kind of reaction. An estimated million kilograms of aldrin and related cyclodiene Lîngă Tine - Orchestra Richard Oschanitzky - Bossanova were produced between and There are multiple available forms of aldrin.
One of these is the isomer isodrinwhich cannot be found in nature, but needs to be synthesized like aldrin. When aldrin enters the human body or the environment it is rapidly converted to dieldrin. Degradation by ultraviolet radiation or microbes can convert dieldrin to photodieldrin and aldrin to photoaldrin.
Even though many toxic effects of aldrin have been discovered, the exact mechanisms underlying the toxicity Teardrops And Heartaches - The New Direction - The New Direction yet to be determined.
The only toxic aldrin induced process that is largely understood is that of neurotoxicity. One of the effects that intoxication with aldrin gives rise to is neurotoxicity. Studies have shown that aldrin stimulates the central nervous system CNSwhich may cause hyperexcitation and seizures.
One of the mechanisms uses the Detonation - Aldrin - Singapore Tribal of aldrin to inhibit brain calcium ATPases. However, when aldrin inhibits these pumps, the intracellular calcium levels rise.
This results in an enhanced neurotransmitter release. The second mechanism makes use of aldrin's ability to block gamma-aminobutyric acid GABA activity.
By blocking this receptor, chloride is unable to move into the synapse, which prevents hyperpolarization of neuronal synapses. Therefore, the synapses are more likely to generate action potentials. The metabolism of oral aldrin exposure has not been studied in humans. However, animal studies are able to provide an extensive overview of the metabolism of aldrin.
This data can be related to humans. Biotransformation of aldrin starts with epoxidation of aldrin by mixed-function oxidases CYP which forms dieldrin. This conversion happens mainly in the liver. Dieldrin can then be directly oxidized by cytochrome oxidases, which forms 9-hydroxydieldrin. An alternative for oxidation involves the opening of the epoxied ring by epoxied hydrases, which forms the product 6,7-trans-dihydroxydihydroaldrin.
Considering the toxicokinetics of aldrin in the environment, the efficacy of the compound has been determined. In addition, the adverse effects after exposure to the aldrin are demonstrated, indicating the risk regarding the compound. The ability of aldrin, in its use for the control of termites, is examined in order to determine the maximum response when applied. In Detonation - Aldrin - Singapore Tribal researchers Detonation - Aldrin - Singapore Tribal aldrin and dieldrin on terrains with rats known to carry chiggersat a rate of 2.
The Aldrin and Dieldrin treatment demonstrated a decrease of 75 times less chiggers on rats for Dieldrin treated terrains and 25 times less chiggers on the rats when treated with Aldrin.
Exposure of Aldrin to the environment leads to the localization of the chemical compound in the air, soil, and water. This biomagnification can lead to a high concentrations in their fat.
There are some reported cases Detonation - Aldrin - Singapore Tribal workers who developed anemia after multiple dieldrin exposures.
However the main adverse effect of Aldrin and Dieldrin is in relationship to the central nervous system. The toxicity of aldrin Skin (25) - Skin dieldrin is determined by the results of several animal studies. Reports of a significant increase in workers death in relation to aldrin has not been found, although death by anemia is reported in some cases after multiple exposure to Aldrin.
Immunological tests linked an antigenic response to erythrocytes coated with dieldrin in those cases. In addition to these studies, breast cancer risk studies were performed demonstrating a significant increased breast cancer risk. After comparing blood concentrations to number of lymph nodes and tumor size a 5-fold higher risk of death was determined, comparing the highest quartile range in the research to the lower quartile range.
Most of the animal studies done with aldrin and dieldrin used rats. High doses of aldrin and dieldrin demonstrated neurotoxicitybut in multiple rat studies also showed Detonation - Aldrin - Singapore Tribal unique Detonation - Aldrin - Singapore Tribal of the mouse liver to dieldrin induced hepatocarcinogenicity.
Like related polychlorinated pesticides, aldrin is highly lipophilic. Its solubility in water is only 0. In the U. The substance is banned from use for plant protection by the EU. For fish however, it is extremely toxic, with an LC50 of 0. In the US, aldrin is considered a potential occupational carcinogen by the Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health ; these agencies have set an occupational exposure limit for dermal exposures at 0.
It is classified as an extremely hazardous substance in the United States as defined in Section of the U. From Wikipedia, the free encyclopedia. For other uses, see Aldrin disambiguation. HHDN  octalene . CAS Number. Interactive image. PubChem CID. Chemical formula. Solubility in water. GHS hazard statements. GHS precautionary statements. LD 50 median dose. LC Lo lowest published. PEL Permissible. REL Recommended. IDLH Immediate danger. Retrieved Basic Organic Chemistry, Part 5 Industrial products.
London: Wiley. Cyclisations and rearrangements in the isodrin? Journal of the Chemical Society Resumed : — The Indian Journal of Medical Research. Journal of Toxicology and Environmental Health. Journal of the Air Pollution Control Association. March Biochemical Pharmacology. December Environmental Research. Bibcode : ER June Food and Cosmetics Toxicology. Journal of Economic Entomology. November Journal of Agricultural and Food Chemistry.
Occupational and Environmental Medicine. Toxicology and Applied Pharmacology. Journal of Clinical Epidemiology. Industrial Health. Anaesthesia and Intensive Care. October Detonation - Aldrin - Singapore Tribal
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